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Provera (medroxyprogesterone usp) Product Info

Medroxyprogesterone is used for:

Treating certain menstrual problems or uterine problems (eg, abnormal bleeding, endometrial hyperplasia). It may also be used for treating certain conditions as determined by your doctor.

Medroxyprogesterone is a progestin hormone. It works by altering the lining of the uterus.

Do NOT use Medroxyprogesterone if:

• you are allergic to any ingredient in Medroxyprogesterone
• you have vaginal bleeding of unknown cause, or if you have a history of blood clots, bleeding in the brain (eg, stroke), liver problems, or breast or genital cancer.
• you are pregnant or may be pregnant.

Contact your doctor or health care provider right away if any of these apply to you.

Before using Medroxyprogesterone :

Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

• if you are planning to become pregnant or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have diabetes, seizures (eg, epilepsy), migraines, asthma, heart problems, kidney problems, or a history of depression.

Some MEDICINES MAY INTERACT with Medroxyprogesterone. Tell your health care provider if you are taking any of the following medicines.

• Rifampin because effectiveness of Medroxyprogesterone may be decreased.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Medroxyprogesterone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Medroxyprogesterone :

Use Medroxyprogesterone as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Medroxyprogesterone may be taken with or without food.
• Medroxyprogesterone comes with an additional patient leaflet. Read it carefully and reread it each time you get Medroxyprogesterone refilled.
• Take Medroxyprogesterone at the same time every day, with doses not more than 24 hours apart.
• If you miss a dose of Medroxyprogesterone , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Medroxyprogesterone.

Important safety information:

• Medroxyprogesterone may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Medroxyprogesterone. Using Medroxyprogesterone alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Medroxyprogesterone may cause dark skin patches on your face. Exposure to the sun may make these patches darker. If patches develop, use a sunscreen or protective clothing when exposed to the sun, sunlamps, or tanning booths.
• Diabetes patients - Medroxyprogesterone may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
• Medroxyprogesterone is not recommended for use in CHILDREN; safety and effectiveness have not been confirmed.
• PREGNANCY and BREAST-FEEDING: Do not use Medroxyprogesterone if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. Medroxyprogesterone is excreted in breast milk. If you are or will be breast-feeding while you are using Medroxyprogesterone , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Medroxyprogesterone :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Acne; changes in menstrual flow, including breakthrough bleeding, spotting, or missed periods; dizziness; drowsiness; fever; headache; hot flashes; nausea; nervousness; pain; rash; sleeplessness; stomach pain; weakness; weight gain or loss.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; depression; lumps in the breast or under the armpits; partial or complete loss of vision or changes in vision; shortness of breath; slurred speech; sudden loss of coordination; sudden or severe headache; swelling of fingers or ankles; tenderness, pain, or swelling of the calf; weakness, numbness, or pain in the arms or legs; yellowing of the skin or eyes.

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